The church of San Luca Evangelista is dedicated to the patron of Praiano, it keeps the remainings of the Saint (reliquia), together with some noticeable works from the '500 by Lama, the wooden altar and the "Madonna col Bambino tra i santi Luca e Francesco".

The church of San Luca in Praiano is also renouned for its dome decorated with vietri majolica, according to the most typical local tradition.

San Luca is internally divided in three navate, the main altar and six minor chapels.